Endoscopic Third Ventriculostomy: A Comparable Alternative to Ventriculoperitoneal Shunt for Obstructive Hydrocephalus Secondary to Infratentorial Tumors

Abstract

Objective: To establish ETV  as a comparable alternative to ventriculoperitoneal shunt for obstructive hydrocephalus secondary to infratentorial tumors.

Methods: 40 Patients with infratentorial tumors presenting with hydrocephalus were enrolled in a prospective descriptive case series. Symptoms, neurological examinations, CT scan and intra-operative findings were used detect the complications at 03 months.

Results:   Mean age = 31.98 ± 15.24 years, female to male ratio of 1:1.2. The KPS score of the participants was ? 70% and ETVSS ?80. Average operative mean time was 21 ± 2.82 minutes. Within first week, the improvement in symptoms was recorded (CI=95%): headache – 87.5% (p < 0.001), nausea vomiting - 84% (p < 0.001), gait disturbance – 59.3% (p=0.442) seizures improvement -100% (p=0.016) and urinary incontinence – 66.7% (p=0.687). Radiological improvement in hydrocephalus on CT scan was seen in one patient within 24 hours – 2.5% (p= <0.001), 12.5% (p<0.001) after two weeks and 87.5% (p= <0.001) after three months post-operatively (CI 95%). Most common of these were decrease in the size of third ventricle and decrease in the size of frontal horns of lateral ventricles.  However, complete resolution of radiologic features was observed in two patients only 5% (p<0.001). However, complete resolution of radiologic features was not observed in any patient. No intra-operative or post-operative complication of ETV was recorded.

Conclusion: ETV is a quick and safe method for CSF diversion in obstructive hydrocephalus alleviating the need for placement of VP shunt hardware, thus eliminating foreign body related cranio-abdominal complications.