Radiologic–Histopathologic: Correlation of Intracranial Tumors Operated in a Tertiary Care Hospital: A Prospective Study
DOI:
https://doi.org/10.36552/pjns.v27i1.813Abstract
Objective: This study aims to Correlate the pre-operative MRI diagnosis with proven histopathological diagnosis of consecutively operated brain tumors.
Material and Methods: The study included 51 cases of brain tumors, evaluated and operated on during the 4 months study period at Jinnah Postgraduate Medical Centre, Karachi. Data of the cases were collected from all patients operated and tissue diagnosis was correlated with MRI brain with contrast (Radiological Diagnosis).
Results: We evaluated 51 cases of brain tumors with a male preponderance. The most common tumors were meningiomas (15 cases, 29.4%). The second most frequent brain tumors were Gliomas (13 cases, 25.4%). Other common tumors were Pituitary Adenoma (7 cases, 13.7%), Pilocytic Astrocytoma (3 cases – 5.8%), Colloid cyst (2 cases – 3.8%), Non-Keratinizing Squamous Cell Carcinoma (2 cases – 3.8%). Preoperatively, Initial diagnosis on MRIs was proven with histopathologic examinations in 14/17 Meningiomas (82.35%), 12/13 Gliomas (92.3%), 7/7 Pituitary Adenomas (100%), 2/2 Colloid (100%), 1/1 Abscess (100%,) 0/2 Fungal mass (0%), 1/1 Chondrosarcoma (100%), ½ Medulloblastoma (50%), 1/1 Pilocytic astrocytoma (100%), 1/1 Ependymoma (100%), 0/1 Hemangiopericytoma (0%), 0/1 Clival chordoma (0%), 0/1 Craniopharyngioma. Overall, MRIs had a fairly accurate rate to diagnose brain neoplasms (78.4%).
Conclusion: Most of the tumors in this study were benign. Meningiomas were the most frequent tumors followed by Gliomas, Pituitary adenomas, and Vestibular schwannomas. MRIs can help diagnose brain tumors preoperatively with fair accuracy.
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