Analysis of Bilateral Stereotactic Pallidotomy in Patients Presenting with Generalized Dystonia
Keywords:Stereotactic pallidotomy, Burke-Marsden-Fahn Dystonia Scale score, generalized dystonia
Objective: To find the improvement with stereotactic pallidotomy. The main aim of the study was to assess the outcome based on mean change in Burke-Marsden-Fahn Dystonia Scale (BMFDS) score after stereotactic pallidotomy in patients presenting with generalized dystonia.
Material & Methods: Quasi-experimental study was conducted over five years at Unit II, Department of Neurosurgery, Lahore General Hospital, Lahore. A total of 16 patients 9 were males and 6 were female meeting inclusion criteria of age 20-70years of either gender presenting with generalized dystonia for at least 6 months. Patients underwent stereotactic pallidotomy. Furthermore, Patients with coagulopathies (PT, apt > 4 sec deranged), Patients with a history of trauma, Patients with CVA (on history), and patients having intracranial pathology (trauma/hematoma) were excluded. BMFDS score was noted at baseline and after 3 months of surgery, and change in BMFDS was noted. The questionnaire was used to collect information. SPSS Version 21 was used to examine the data that had been gathered.
Results: The patients' average age was 47.35 and 14.40 years. There were 19 (31.67%) males and 41 (68.33%) females. The mean duration of dystonia was 15.43 ± 6.13 months. At baseline, the mean BMFDS was 49.67 ± 5.69 which was reduced to 18.03 ± 3.35. The mean change in BMFDS was 31.63 ± 6.38. There was a significant change in BMFDS (p < 0.05).
Conclusion: Hence, in patients with generalized dystonia, stereotactic pallidotomy is beneficial in lowering the BMFDS score by more than 50%.
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