Predictive Role of Tumor Dimensions and Body Mass Index in The Development of Postoperative Diabetes Insipidus Following Pituitary Adenoma Resection: Analysis of 209 Consecutive Cases

Abstract

Objective:  This study examines the outcomes of tumor size, dimensions, and patients’ body mass index (BMI) on the postoperative DI.

Material and Methods:  This study was done on 209 patients who met the inclusion criteria. They were counseled and comprehensively informed about the study. The DI was labeled according to the operational definition. The DI was managed as per ward protocol. All the data was recorded. All the surgeries were done by one surgical team, and all the labs were done from one lab, i.e., hospital lab.

Results:  Out of 209 patients, 1.9% (n = 4) were between 5 and 30 years of age, and 98.1% (n = 205) were between 31 and 60 years of age. The mean age was 41.45 ± 6.47 years. The distribution of the size of the tumor was 2.69 ± 0.756 cm, and the distribution of BMI was 26.00 ± 1.954 kg/m2.  Out of 209 patients, 61.2% (n = 128) were male, whereas 38.8% (n=81) were female. The distribution of DI among patients undergoing endoscopic transsphenoidal surgery was 25.4% (n=53).

Conclusion:  We found that DI among patients undergoing endoscopic transsphenoidal surgery was 25.4% (n=53).  Therefore, post-operative DI is one of the common complications after pituitary surgery