Intracranial Meningioma; Assessment of Tumor Size and Clinical Feature on First Presentation


  • Haris Hamid Department of Neurosurgery, Jinnah Postgraduate Medical Center, Karachi-Pakistan
  • Iram Bokhari Department of Neurosurgery, Jinnah Postgraduate Medical Center
  • Arfa Qasim Department of Neurosurgery, Jinnah Postgraduate Medical Center, Karachi
  • Bushra Maqsood Department of Neurosurgery, Jinnah Postgraduate Medical Center, Karachi
  • Asra Aslam Department of Neurosurgery, Jinnah Postgraduate Medical Center, Karachi
  • Farrukh javed Department of Neurosurgery, Jinnah Postgraduate Medical Center, Karachi



meningioma, excision, Space Occupying Lesion, supratentorial, Clinical features


Objective:  To assess the tumor size of intracranial meningioma on first presentation and their clinical features.

Materials & Methods:  A prospective review of patients undergoing meningioma resection at the Neurosurgery department, Jinnah Postgraduate Medical Center, Karachi was performed. The clinical records and imaging studies of 43 patients with intracranial meningiomas were analyzed. The data was collected for tumor size, location, first symptom, and clinical features.

Results:  There were 31 (72.1%) female and 12 (27.9%) male patients with a mean age of 45.6 years (std: 8.18 years). convexity and Parasagittal meningiomas had the highest frequency (32.6% and 30.2% respectively). The average tumor size was greater than 60mm (44.2%). Skull base tumors presented with a size of more than 60mm (60.0%), followed by convexity meningiomas (57.1%). The most common initial symptom was headache (46.5%) followed by seizures (11.6%). The patients presenting with a duration greater than 24 months (32.6%) had a size greater than 60mm (57.1%). Convexity and skull base meningiomas presented lately greater than 24 months of duration (50%), however, parasagittal meningioma generally presented earlier in less than 6 months of duration 53.8%.

Conclusion:  Tumor size location, and clinical features at the first presentation are interlinked. Larger tumors were found on the first presentation, with headache and seizure being the most common clinical features. The location also contributed to the early or late presentation of meningioma patients. The association shown between the size and first symptom may be explained by a symptom's tolerance, location, and ongoing medical treatment.

Keywords:  Meningioma, Excision, Space Occupying Lesion, Supratentorial, Clinical Features


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